solubility prediction of anthracene in non-aqueous solvent mixtures using jouyban-acree model

نویسندگان

abolghasem jouyban

faculty of pharmacy and drug applied research centre, tabriz university of medical sciences, tabriz, iran hassan jalilzadeh

kimia research institute, tabriz, iran maryam khoubnasabjafari

kimia research institute, tabriz, iran william e. acree jr.

department of chemistry, university of north texas, denton, usa

چکیده

a quanitative structure property relationship was proposed to calculate the binary interaction terms of the jouyban-acree model using solubility parameter, boiling point, vapour pressure and density of solvents. the applicability of the proposed method for reproducing solubility data of anthracene in binary solvents has been evaluated using 116 solubility data sets collected from the literature. the mean percentage deviation (mpd) of experimental and calculated solubilities has been computed as a measure of accuracy and the mpd of the proposed method was ~ 6 %. the accuracy of the method was compared with that of a previously reported method where the mpd was ~ 12 % and the mean differences between proposed and previous methods was statistically significant.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Solubility Prediction of Anthracene in Non-Aqueous Solvent Mixtures Using Jouyban-Acree Model

      A quanitative structure property relationship was proposed to calculate the binary interaction terms of the Jouyban-Acree model using solubility parameter, boiling point, vapour pressure and density of solvents. The applicability of the proposed method for reproducing solubility data of anthracene in binary solvents has been evaluated using 116 solubility data sets collected from the lite...

متن کامل

In silico prediction of drug solubility in water-ethanol mixtures using Jouyban-Acree model.

PURPOSE A predictive method was proposed to predict solubility of drugs in water-ethanol mixtures at various temperatures based on the Jouyban-Acree model. The model requires the experimental solubility data of the drug in mono-solvent systems. METHODS The accuracy of the proposed prediction method was evaluated using collected experimental solubility data from the literature. The proposed me...

متن کامل

Solubility of Naproxen in Polyethylene Glycol 200 + Water Mixtures at Various Temperatures

The solubility of naproxen in binary mixtures of polyethylene glycol 200 (PEG 200) + water at the temperature range from 298.0 K to 318.0 K were reported. The combinations of Jouyban-Acree model + van’t Hoff and Jouyban-Acree model + partial solubility parameters were used to predict the solubility of naproxen in PEG 200 + water mixtures at different temperatures. Combination of Jouyban-Acree m...

متن کامل

Solubility of Naproxen in Polyethylene Glycol 200 + Water Mixtures at Various Temperatures

The solubility of naproxen in binary mixtures of polyethylene glycol 200 (PEG 200) + water at the temperature range from 298.0 K to 318.0 K were reported. The combinations of Jouyban-Acree model + van't Hoff and Jouyban-Acree model + partial solubility parameters were used to predict the solubility of naproxen in PEG 200 + water mixtures at different temperatures. Combination of Jouyban-Acree m...

متن کامل

Solubility of Naproxen in Polyethylene Glycol 200 + Water Mixtures at Various Temperatures

The solubility of naproxen in binary mixtures of polyethylene glycol 200 (PEG 200) + water at the temperature range from 298.0 K to 318.0 K were reported. The combinations of Jouyban-Acree model + van’t Hoff and Jouyban-Acree model + partial solubility parameters were used to predict the solubility of naproxen in PEG 200 + water mixtures at different temperatures. Combination of Jouyban-Acree m...

متن کامل

Solubility of Acetaminophen and Ibuprofen in Polyethylene Glycol 600, N-Methyl Pyrrolidone and Water Mixtures

The solubility of acetaminophen and ibuprofen in binary and ternary mixtures of N-methyl pyrrolidone, polyethylene glycol 600 and water at 25 °C were determined and the solubilities are mathematically represented by the Jouyban–Acree model. The density of the solute-free solvent mixtures was measured and employed to train the Jouyban–Acree model and then the densities of the saturated solutions...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
iranian journal of pharmaceutical sciences

جلد ۲، شماره ۲، صفحات ۷۳-۸۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023